The endocannabinoid system (SEC) It is a complex biological system that is found throughout the human body and plays a crucial role in the regulation of various physiological functions. Discovered in the 1990s, this system helps maintain balance or "homeostasis" in the body, controlling as important aspects as mood, appetite, sleep and response to pain.
In today's article, from Grow Industry, online store of crop products, we tell you everything you should know about what the endocannabinoid system is and how it works.
What exactly is the endocannabinoid system?
Let's start at the beginning ... the endocannabinoid system is composed of a series of cell receptors, endogenous molecules (endocannabinoides) and enzymes that regulate its function. Its main objective is to ensure that the body works in a balanced way, activating when something is out of balance, like pain or stress, and helping to restore balance. Although this system is better known for its interaction with cannabinoids present in cannabis, such as the THC and the CBD, also plays a fundamental role in daily well -being.

What is the endocannabinoid system composed?
He Endocannabinoid system It consists of three main elements:
- Endocannabinoides: These are molecules produced by the body that are similar to cannabinoids present in cannabis, such as the Anandamide and the 2-AG. These molecules bind to cannabinoid receptors to regulate specific physiological functions.
- Cannabinoid receptors: They are proteins that are found on the surface of the cells and are divided into two types: CB1 and CB2. CB1 receptors are more present in the central nervous system, while CB2 are mainly in the immune and peripheral system.
- Enzymes: They are responsible for decomposing endocannabinoids once they have fulfilled their function. The two main enzymes are Faah, that degrades the anandamide, and Magl, which breaks down the 2-AG.
These components work together to regulate a wide range of processes, ensuring that physiological functions maintain their appropriate balance.
Where are cannabinoid receptors?
CB1 cannabinoid receptors
The CB1 receptors They are mainly in the central nervous system (brain and spinal cord), but may also be present in other body tissues, such as the liver, digestive system and lungs. These receptors are responsible for the psychoactive effects generated by the consumption of THC, the main psychoactive compound of cannabis. By joining these receptors, THC can alter the perception of pain, memory and mood, among other functions.
In the brain, CB1 receptors They regulate neurotransmitters that influence anxiety, stress and feeling of pleasure. For this reason, many cannabinoid -based therapies are focused on this receiver, especially to treat chronic pain and neurological disorders.
CB2 cannabinoid receptors
The CB2 receptors are distributed mainly in the Immune system and in peripheral cells. Its main function is Modulate inflammation and immune response. Unlike CB1 receptors, CB2 do not generate psychoactive effects, which makes interest in cannabinoids that interact with this receiver, such as CBD, be increasing in the treatment of autoimmune and inflammatory diseases.
When CB2 are activated, especially by the CBD Or endocannabinoides, the body can reduce its inflammatory response, helping to relieve conditions such as arthritis, chronic inflammation and diseases related to the immune system.
What function does the endocannabinoid system have?
He Endocannabinoid system plays a key role in the Regulation of various physiological functions Like appetite, pain, memory and immune response. Its main mission is to maintain homeostasis, which means that it balances the responses of the body when imblages are presented, as in the case of inflammation or pain. When the endocannabinoid system is activated, it ensures that the body regulates these processes efficiently, maintaining internal stability.
How does the CBD interact in the endocannabinoid system?
He CBD o Cannabidiol, one of the main cannabis compounds, interacts with the endocannabinoid system in a unique way. Unlike THC, the CBD does not directly join CB1 or CB2 receptors. Instead, it acts as a indirect modulator, promoting the activation of the natural endocannabinoids of the body, such as anandamide, so that they can do their job more efficiently.
The CBD also inhibits the FAAH enzyme, which causes an increase in anandamide levels, known as the "happiness molecule." This can contribute to a greater sense of well -being without the psychoactive effects caused by THC. In addition, the CBD can influence other receptors, such as serotonin receptors, which explains why it is so effective for reduce anxiety and stress.
On the other hand, the CBD has the ability to Modulate inflammation through CB2 receptors, being effective to treat chronic inflammatory conditions. Its ability to interact with the immune system also makes it a promising tool in the treatment of autoimmune diseases. In short, the CBD It enhances the endocannabinoid system without psychoactive effects, helping the body to find its natural balance.
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